Postoperative Pain Management in Rhinoplasty

Not Recruiting

Trial ID: NCT03584152


The primary purpose of the study is to determine adequacy of postoperative pain control after nasal surgery in patients prescribed Acetaminophen (325mg) + Hydrocodone (5mg) compared to Acetaminophen(325mg) + Ibuprofen (200mg)for a period of 5 days after nasal surgery. To assess the degree of pain, the participants will score the intensity of their pain on a visual analog scale(VAS)of 0-100points (0- no pain and 100- most severe pain), preoperatively and postoperatively (to be documented before each dose) for the duration of the prescribed medications . Additionally, the study will also seek to track: 1. The total number of pills each patients consume from the prescribed 5 day regimen. 2. Any associated side effects. 3. Additional pain medications prescribed in case of inadequate pain control, postoperatively.

Official Title

Postoperative Pain Management in Rhinoplasty: A Randomized Controlled Trial

Stanford Investigator(s)

Sam P. Most, MD, FACS
Sam P. Most, MD, FACS

Professor of Otolaryngology - Head & Neck Surgery (OHNS)


Inclusion Criteria:

   - Minimum age of 18 years

   - Able to speak and understand english.

   - Undergoing rhinoplasty for cosmetic purposes

   - Undergoing rhinoplasty for treatment of nasal obstruction

Exclusion Criteria:

   - Less than 18 years of age

   - Cannot speak and understand english

   - Patients who have undergone nasal surgery in the past

   - Patients not undergoing nasal surgery

   - Women will be excluded if they are either pregnant or lactating as this population
   does not undergo nasal surgery at our center.

   - Patients with any known allergies to the class of pain medications used in the study.

Please note: Any person interested in this clinical trial should contact the Facial Plastic
and Reconstructive Surgery clinic at (650) 736 - FACE (3223) to schedule a consultation
with Dr. Sam P. Most to assess their eligibility for the trial. Please note, enrolling in
the clinical trial will not entitle the participant to a waiver of charges associated with
undergoing nasal surgery.


drug: Norco 5Mg-325Mg Tablet

drug: Tylenol 325Mg Caplet

drug: Ibuprofen 200 mg

Not Recruiting

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Cherian K Kandathil, MD