Pain Catastrophizing and Prescription Opioid Craving


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Trial ID: NCT04097743


Adherence to prescription opioid and opioid tapering as indicated are critical for safe chronic opioid therapy for chronic pain, but this can be difficult for patients experiencing prescription opioid craving. Because pain catastrophizing is proposed as a possible treatment target by our and others' preliminary results, the proposed study aims to determine whether pain catastrophizing is a treatment target to reduce prescription opioid craving and to investigate whether negative affect and stress hormones are potential mediators. The findings from the current study will inform whether a psychology intervention to lower pain catastrophizing will reduce opioid craving, and whether psychological and physical distress as well as cognitive function will be potential mediators of the treatment effect.

Official Title

Effect of Pain Catastrophizing on Prescription Opioid Craving

Stanford Investigator(s)

Dokyoung Sophia You, PhD

Clinical Assistant Professor, Anesthesiology, Perioperative and Pain Medicine


Inclusion Criteria:

   - At least 18 years

   - Chronic pain ( > 3months)

   - Prescription opioid use (>3 months)

Exclusion Criteria:

   - Current diagnosis of cancer

   - Concurrent psychological therapy

   - Other severe psychiatric conditions (schizophrenia, delusional disorder, psychotic
   disorder, dissociative disorder, and active suicidality)

   - Any skin conditions on the hand (pain testing site)

   - Non-English speaker

   - No access to email or smart phone


behavioral: Coping Statement


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Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305