Prostatic Artery Embolization for the Treatment of Lower Urinary Tract Symptoms in Prostate Cancer Patients Undergoing Radiation Therapy

Inclusion Criteria:

* Age ≥ 40 years and ≤ 90 years old
* Prostate volume ≥ 40 mL and ≤ 300 mL
* Biopsy proven prostate cancer undergoing radiation therapy
* Diagnosis of moderate to severe lower urinary tract symptoms (LUTS) defined as at least one of the following:

1. IPSS ≥ 12 or dependent on urinary catheterization, or
2. IPSS Quality of Life (QoL) assessment ≥ 3, and
3. Qmax ≤ 12 mL/sec
* Ability to understand and willingness to sign the written consent

Exclusion Criteria:

* Neurogenic bladder disorder due to multiple sclerosis, Parkinson's disease, spinal cord injury, diabetes, etc., as demonstrated on urodynamic testing.
* Detrusor muscle failure, urethral stenosis, or urinary obstruction due to causes other than prostatic obstruction, as demonstrated on urodynamic testing
* Bladder diverticula greater than 5 cm or bladder stones greater than 2 cm
* Other active urogenital cancer
* Baseline serum creatinine greater than 2 mg/dL
* Evidence of tortuous or atherosclerotic blood vessels
* Coagulation disturbances not normalized by medical treatment
* Allergy to iodinated contrast agents not responsive to steroid premedication regimen