Recovery of Ventilation After Anesthesia for Laparoscopic Nephrectomy

Not Recruiting

Trial ID: NCT04723433


The purpose of this randomized, controlled feasibility investigation is to characterize pharmacologically induced ventilatory depression after anesthesia and examine how is affected by the amount of supplemental oxygen patients are receiving in the immediate postoperative period.

Official Title

Recovery of Ventilation After General Anesthesia for Robotic-assisted Laparoscopic Nephrectomy: The Effect of Conservative Versus Liberal Oxygen Supplementation - A Feasibility Study

Stanford Investigator(s)

Anthony G. Doufas, M.D., Ph.D.
Anthony G. Doufas, M.D., Ph.D.

Professor of Anesthesiology, Perioperative and Pain Medicine


Inclusion Criteria:

   - American Society of Anesthesiologists (ASA) physical status I-III

   - Body mass index (BMI) less than 40 kg/m2

   - Scheduled to undergo robotic-assisted radical laparoscopic nephrectomy.

Exclusion Criteria:

   - Patients with a diagnosis of chronic obstructive pulmonary disorder (COPD), severe
   neurological, cardiopulmonary, psychiatric, or untreated thyroid disorder

   - Chronic pain condition that is being treated with opioids

   - Patients with a hematocrit lower than 30% at the end of surgery, or those with an
   excessive blood loss, requiring transfusion of blood products during their surgery,
   will be also excluded from the study.


other: Oxygen gas -Conservative

other: Oxygen gas -Liberal

Not Recruiting

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Anthony Doufas, MD, PhD