Surgical Weight-Loss to Improve Functional Status Trajectories Following Total Knee Arthroplasty (SWIFT Trial)

Inclusion Criteria:

   - Age 22-75 years.

   - Subject is diagnosed with Non-inflammatory Degenerative Joint Disease(NIDJD).

   - Subject is diagnosed with Morbid Obesity (Body Mass Index ≥ 40 kg/m2 or >35 kg/m2 with
   qualifying comorbid conditions such as obstructive sleep apnea or diabetes).

   - Subject is a suitable candidate for cemented primary TKA with either resurfaced or
   non-resurfaced patellae.

   - Subject is currently not bedridden.

   - Subject, in the opinion of the Clinical Investigator, is able to understand this
   clinical investigation and co-operate with investigational procedures.

   - Subject has given voluntary, written informed consent to participate in this clinical
   investigation.

   - Subject is comfortable with speaking, reading, and understanding questions and
   providing responses in an available translated language.

Exclusion Criteria:

   - Subject has undergone THA or contralateral knee within the past 6 months.

   - Subject has had a contralateral amputation.

   - Subject requires simultaneous bilateral TKA.

   - Previous partial knee replacement (unicompartmental, bicompartmental or patellofemoral
   joint replacement), patellectomy, high tibial osteotomy or primary TKA in affected
   knee.

   - Subject is currently experiencing radicular pain from the spine.

   - Subject was diagnosed with fibromyalgia that is currently being treated with
   prescription medication.

   - Subject has significant neurological or musculoskeletal disorders or disease that may
   adversely affect gait or weight bearing (e.g. muscular dystrophy, multiple sclerosis,
   Charcot disease).

   - Subject is suffering from inflammatory arthritis (e.g. rheumatoid arthritis, juvenile
   rheumatoid arthritis, psoriatic arthritis, systemic lupus erythematosus, etc.).

   - Subject has had previous bariatric surgery.

   - Subject is medically or psychologically not suitable to undergo surgery.

   - Subject is a known drug or alcohol abuser or has a psychological disorder that could
   affect their ability to complete patient reported questionnaires.

   - Subject has a medical condition with less than 2 years of life expectancy.

   - Subject has participated in an IDE/IND clinical investigation with an investigational
   product in the last three months.

   - Subject is not comfortable with speaking, reading, and understanding questions and
   providing responses in an available translated language.