Trial of Cervical Ripening and Labor Induction Using Misoprostol With or Without Intravaginal Isosorbide Mononitrate

Not Recruiting

Trial ID: NCT00374621

Purpose

The purpose of this study is to determine the efficacy and safety of the addition of intravaginal isosorbide mononitrate to an established protocol of oral misoprostol for cervical ripening and labor induction.

Official Title

Randomized Clinical Trial of Cervical Ripening and Labor Induction Using Stepwise Oral Misoprostol With or Without Intravaginal Isosorbide Mononitrate

Stanford Investigator(s)

Yasser El-Sayed, Professor
Yasser El-Sayed, Professor

Charles B. and Ann L. Johnson Professor in the School of Medicine and Professor, by courtesy, of Pediatrics (Neonatology) and of Surgery

Eligibility

Inclusion Criteria::

* Pregnant women
* 18 years of age or greater
* Singleton pregnancy between 32-42 weeks gestation requiring labor induction
* Membranes must be intact

Exclusion Criteria:

* Ruptured membranes
* Gestational age less than 32 weeks
* Non-reassuring fetal heart rate tracing

Intervention(s):

drug: Misoprostol with or without isosorbide mononitrate

Not Recruiting

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Yasser El-Sayed
6507233198