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Transversus Abdominis Plane Block in Microsurgical Breast Recon w/Abdominal Free Flap in Breast CA
Not Recruiting
Trial ID: NCT02601027
Purpose
The primary objective is to determine if pre-operative transversus abdominis plane (TAP)
nerve blocks by continued infusion of local anesthetic post-operatively affects
post-operative narcotic usage, as compared to a placebo TAP block, after breast
reconstruction surgery.
Official Title
A Phase III Study of Pre-operative Transversus Abdominis Plane Blocks Using the Nimbus Ambulatory Infusion System in Patients Undergoing Abdominal Free Flap-based Breast Reconstruction
Stanford Investigator(s)
Gordon K. Lee, M.D.
Professor of Surgery (Plastic and Reconstructive Surgery)
Dung Nguyen
Clinical Professor, Surgery - Plastic & Reconstructive Surgery
Eligibility
Inclusion Criteria
- Prior diagnosis or presumed diagnosis of breast cancer or undergoing prophylactic
treatment.
- Greater than 18 years old.
- Female.
- Undergoing microsurgical breast reconstruction with abdominal free flap.
- Ability to understand and the willingness to sign a written informed consent document.
Exclusion Criteria
- True allergy to local anesthetics or opioids.
- History of addiction to narcotics within the last 24 months
- History of chronic pain on opioids within the last 24 months.
- Specific mental health issues such as schizophrenia or bipolar disorder.
- Patients who are pregnant.
Intervention(s):
drug: bupivacaine infusion
drug: acetominophen
drug: Hydromorphone
drug: Oxycodone
drug: Ondansetron
device: Nimbus Infusion Pump IV Administration
procedure: Transversus Abdominis Plane (TAP) block
Not Recruiting
Contact Information
Stanford University
School of Medicine
300 Pasteur Drive
Stanford,
CA
94305
Afaaf Shakir