Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) Use in Pediatric Procedures

Not Recruiting

Trial ID: NCT03430206

Purpose

THRIVE (Transnasal Humidified Rapid-Insufflation Ventilatory Exchange) refers to the use of high-flow nasal cannula to augment the ability to oxygenate and ventilate a patient under general anesthesia. The use of high-flow nasal cannula oxygen supplementation during anesthesia for surgical procedures has been a recent development in the adult population, with limited data analyzing the pediatric population. This study will determine whether high flow nasal cannula oxygen supplementation during surgical or endoscopic procedures can safely prevent desaturation events in children under anesthesia.

Official Title

Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) Use in Pediatric Procedures

Stanford Investigator(s)

Thomas Caruso

Clinical Professor, Anesthesiology, Perioperative and Pain Medicine

Samuel Rodriguez, MD

Clinical Professor, Anesthesiology, Perioperative and Pain Medicine

Douglas Sidell, MD
Douglas Sidell, MD

Associate Professor of Otolaryngology - Head & Neck Surgery (OHNS) and, by courtesy, of Pediatrics

Romy Yun

Clinical Associate Professor, Anesthesiology, Perioperative and Pain Medicine

Ellen Wang
Ellen Wang

Clinical Professor, Anesthesiology, Perioperative and Pain Medicine

Eligibility

Inclusion Criteria:

* Pediatric patients less than or equal to 18 years old undergoing general anesthesia for procedures or surgeries at Lucile Packard Children's Hospital.

Exclusion Criteria:

* Pregnancy, absence of parent or legal guardian able to provide written consent for study participation, anatomical or surgical contraindications (epistaxis, basilar skull fractures or abnormalities, nasal surgery or obstruction, nasal fractures, nasal vascular abnormalities), papillomatosis, tracheostomy, emergent surgery for which application of HFNC might delay surgery or might result in increased aspiration risk.

Intervention(s):

device: High-flow nasal cannula

Not Recruiting

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Thomas J Caruso, M.D., M.Ed.
650-723-5728