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Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) Use in Pediatric Procedures

Not Recruiting

Trial ID: NCT03430206

Age - N/A-18 Years Condition - Pediatric Ear, Nose, and Throat, Pediatric Anesthesia Gender - All Accepting Healthy Volunteers - No

Purpose

THRIVE (Transnasal Humidified Rapid-Insufflation Ventilatory Exchange) refers to the use of high-flow nasal cannula to augment the ability to oxygenate and ventilate a patient under general anesthesia. The use of high-flow nasal cannula oxygen supplementation during anesthesia for surgical procedures has been a recent development in the adult population, with limited data analyzing the pediatric population. This study will determine whether high flow nasal cannula oxygen supplementation during surgical or endoscopic procedures can safely prevent desaturation events in children under anesthesia.

Official Title

Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) Use in Pediatric Procedures

Stanford Investigator(s)

Thomas Caruso

Clinical Professor, Anesthesiology, Perioperative and Pain Medicine

Samuel Rodriguez, MD

Clinical Associate Professor, Anesthesiology, Perioperative and Pain Medicine

Douglas Sidell, MD
Douglas Sidell, MD

Associate Professor of Otolaryngology - Head & Neck Surgery (OHNS) and, by courtesy, of Pediatrics

Chi-Ho Ban Tsui

Romy Yun

Clinical Assistant Professor, Anesthesiology, Perioperative and Pain Medicine

Anna H. Messner, MD

Ellen Wang
Ellen Wang

Clinical Associate Professor, Anesthesiology, Perioperative and Pain Medicine

Eligibility


Inclusion Criteria:

   - Pediatric patients less than or equal to 18 years old undergoing general anesthesia
   for procedures or surgeries at Lucile Packard Children's Hospital.

Exclusion Criteria:

   - Pregnancy, absence of parent or legal guardian able to provide written consent for
   study participation, anatomical or surgical contraindications (epistaxis, basilar
   skull fractures or abnormalities, nasal surgery or obstruction, nasal fractures, nasal
   vascular abnormalities), papillomatosis, tracheostomy, emergent surgery for which
   application of HFNC might delay surgery or might result in increased aspiration risk.

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Intervention(s):

device: High-flow nasal cannula

Not Recruiting

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Thomas J Caruso, M.D., M.Ed.
650-723-5728

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