Telehealth 2.0: Evaluating Effectiveness and Engagement Strategies for CPT-Text for PTSD


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Trial ID: NCT05037175


There is a pressing need to increase capacity to treat PTSD related to or exacerbated by the COVID-19 pandemic. Texting-based therapy holds promise to increase capacity and reduce barriers to delivering evidence-based treatments (EBTs), but ongoing engagement in digital mental health interventions is low. This study will compare a texting-based EBT for PTSD to culturally-informed texting-based treatment for PTSD as usual, and it will also compare a unique incentive strategy to typical platform reminders aimed to prevent early discontinuation in therapy. This online study is open to individuals who live in 13 different states.

Official Title

Telehealth 2.0: Evaluating Effectiveness and Engagement Strategies for Asynchronous Texting Based Trauma Focused Therapy for PTSD

Stanford Investigator(s)


Inclusion Criteria:

* Over the age of 18 residing in the United States
* Criterion A event measured by the Life Events Checklist for DSM-5 (LEC-5)
* Significant symptoms of PTSD as evidenced by a score of 33 or above on the PCL-5
* PTSD symptoms that began or increased during the COVID pandemic (per self-report)
* Registered/registering on Talkspace for messaging-based therapy
* Ownership of a personal device for texting
* Residence in a state with therapist capacity on the Talkspace platform

Exclusion Criteria:

* Acute risk for suicidal thoughts and/or behaviors measured by the Columbia Suicide Severity Rating Scale Lifetime-Recent Screen
* Psychosis or substance abuse that requires prioritization of treatment and/or higher level of care


behavioral: CPT-Text

behavioral: Retention Incentive

behavioral: Reminder as Usual

behavioral: Culturally Informed Trauma Treatment (CITT)


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Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Shannon Wiltsey Stirman, PhD