Telehealth 2.0: Evaluating Effectiveness and Engagement Strategies for CPT-Text for PTSD


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Trial ID: NCT05037175


There is a pressing need to increase capacity to treat PTSD related to or exacerbated by the COVID-19 pandemic. Texting-based therapy holds promise to increase capacity and reduce barriers to delivering evidence-based treatments (EBTs), but ongoing engagement in digital mental health interventions is low. This study will compare a texting-based EBT for PTSD to culturally-informed texting-based treatment for PTSD as usual, and it will also compare a unique incentive strategy to typical platform reminders aimed to prevent early discontinuation in therapy.

Official Title

Telehealth 2.0: Evaluating Effectiveness and Engagement Strategies for Asynchronous Texting Based Trauma Focused Therapy for PTSD

Stanford Investigator(s)


Inclusion Criteria:

   - Over the age of 18 residing in the United States

   - Criterion A event measured by the Life Events Checklist for DSM-5 (LEC-5)

   - Significant symptoms of PTSD as evidenced by a score of 33 or above on the PCL-5

   - PTSD symptoms that began or increased during the COVID pandemic (per self-report)

   - Registered/registering on Talkspace for messaging-based therapy

   - Ownership of a personal device for texting

   - Residence in a state with therapist capacity on the Talkspace platform

Exclusion Criteria:

   - Acute risk for suicidal thoughts and/or behaviors measured by the Columbia Suicide
   Severity Rating Scale Lifetime-Recent Screen

   - Psychosis or substance abuse that requires prioritization of treatment and/or higher
   level of care


behavioral: CPT-Text

behavioral: Retention Incentive

behavioral: Reminder as Usual

behavioral: Culturally Informed Trauma Treatment (CITT)


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Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Shannon Wiltsey Stirman, PhD