Wavefront-guided PRK vs Wavefront-optimized PRK

Not Recruiting

Trial ID: NCT02091934


The purpose of the study is to compare the results of PRKK surgery when using wavefront-guided excimer laser treatment compared to wavefront optimized excimer laser treatment in patients with nearsightedness with and without astigmatism

Official Title

A Prospective, Randomized Comparison of Fellow Eyes Undergoing Wavefront-guided PRK Versus Wavefront-optimized PRK Using the Alcon Allegretto Eye-Q 400 Excimer Laser

Stanford Investigator(s)

Edward Manche, MD
Edward Manche, MD

Professor of Ophthalmology


Inclusion Criteria:

   - Subjects age 21 and older with healthy eyes.

   - Nearsightedness between -0.25 diopters and -8.00 diopters with or without astigmatism
   of up to 5.00 diopters.

Exclusion Criteria:

   - Subjects under the age of 21.

   - Excessively thin corneas.

   - Topographic evidence of keratoconus.

   - Ectactic eye disorders.

   - Autoimmune diseases.

   - Pregnant or nursing.

   - Patients must have similar levels of nearsightedness in each eye. They can not be more
   than 2.5 diopter of difference between eyes.

   - Patients must have similar levels of astigmatism in each eye. They can not have more
   than 1.5 diopter of difference between eyes.


procedure: Wavefront-guided PRK

procedure: Wavefront-optimized PRK

Not Recruiting

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Linda Schwartz
650 498-7020