Impact of C-arm CT in Patients With HCC Undergoing TACE: Optimal Imaging Guidance

Not Recruiting

Trial ID: NCT00926536

Purpose

Patients will be enrolled based on presence of HCC and eligibility for TACE. They will be randomized to one of two arms for imaging navigation to the optimal catheter location for chemotherapy injection to treat the first (possibly sole) tumor target. The two arms will be: TACE using C-arm CT supplemented by DSA or DSA only (only DSA images will be used for navigation and tumor vessel tracking). Navigation to subsequent treatment targets in all patients will be done with fluoroscopy, CACT, and DSA, as is standard of care at Stanford University Medical Center, and is not part of the study. Vascular complexity, which affects navigation difficulty and thus the need for imaging, will be assessed separately for use in data analysis by two radiologists on a four-point scale.

Official Title

Impact of C-arm CT in Patients With Hepatocellular Carcinoma (HCC) Undergoing Transhepatic Arterial Chemoembolization (TACE): Optimal Imaging Guidance

Stanford Investigator(s)

Gloria Hwang, MD
Gloria Hwang, MD

Clinical Professor, Radiology

Lawrence "Rusty" Hofmann, MD
Lawrence "Rusty" Hofmann, MD

Professor of Radiology (Interventional Radiology)

David Hovsepian, MD
David Hovsepian, MD

Clinical Professor, Radiology

John D. Louie, MD
John D. Louie, MD

Clinical Professor, Radiology

Daniel Sze, MD, PhD
Daniel Sze, MD, PhD

Professor of Radiology (Interventional Radiology)

WILLIAM T. KUO, MD, FSIR, FCCP, FSVM, FACR, FCIRSE
WILLIAM T. KUO, MD, FSIR, FCCP, FSVM, FACR, FCIRSE

Professor of Radiology (Interventional Radiology)

Nishita Kothary, MD
Nishita Kothary, MD

Professor of Radiology (Interventional Radiology)

Eligibility


Inclusion Criteria:

Patients must be affected by HCC

Patients must be 18 years old or older

Patients must have received an abdominal CT, PET/CT scan or MRI, completed prior to the
TACE procedure.

Ability to understand and the willingness to sign a written informed consent document.

Exclusion Criteria:

Subjects under the age of 18

Pregnant women

Intervention(s):

device: C-arm CT + DSA as needed

device: DSA only

Not Recruiting

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Kamil Unver
6507259810

New Trial Alerts

Receive email alerts when trials open to patients.