Quantitative 13N-Ammonia Cardiac Rest/Stress Digital PET/CT

Not Recruiting

Trial ID: NCT03170817

Purpose

Accurate measurements from a non-invasive test like myocardial perfusion positron emission tomography/ computed tomography (PET/CT) may decrease the need for invasive procedures such as cardiac catheterization.The investigators wish to see if the measurements from cardiac catheterization can be predicted using a non-invasive 13N-NH3 digital PET/CT scan.

Official Title

Quantitative Rest/Stress Cardiac Perfusion Digital PET/CT: Comparison Between Noninvasive Imaging and Invasive Coronary Angiography.

Stanford Investigator(s)

Kip E. Guja, MD PhD

Clinical Assistant Professor, Radiology - Rad/Nuclear Medicine

Guido A. Davidzon
Guido A. Davidzon

Clinical Associate Professor, Radiology - Rad/Nuclear Medicine

Andrei Iagaru
Andrei Iagaru

Professor of Radiology (Nuclear Medicine)

Eligibility

Inclusion Criteria:

* Patient is ≥ 18 years old at the time of the scan
* Patient has known or suspected coronary artery disease
* Patient has had a recent or will be scheduled for a diagnostic coronary angiogram
* Patient provides written informed consent
* Patient is referred for myocardial perfusion scan
* Patient is capable of complying with study procedures
* Patient is able to remain still for duration of imaging procedure (approximately 60 minutes total for both PET/CT)

Exclusion Criteria:

* Patients who are pregnant or breast feeding
* Patients with contraindications to regadenoson

Intervention(s):

drug: N-13 ammonia

drug: Regadenoson

diagnostic_test: Cardiac Perfusion Rest/Stress Digital PET/CT

Not Recruiting

Contact Information

Stanford University
School of Medicine
300 Pasteur Drive
Stanford, CA 94305
Jordan Ciscernos
650-725-6409